Contribution of postnatally formed small beta cell aggregates to functional beta cell mass in adult rat pancreas
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چکیده
منابع مشابه
Neurogenin3 activation is not sufficient to direct duct-to-beta cell transdifferentiation in the adult pancreas.
It remains controversial whether adult pancreatic ducts harbor facultative beta cell progenitors. Because neurogenin3 (Ngn3) is a key determinant of pancreatic endocrine cell neogenesis during embryogenesis, many studies have also relied upon Ngn3 expression as evidence of beta cell neogenesis in adults. Recently, however, Ngn3 as a marker of adult beta cell neogenesis has been called into ques...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 2010
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s00125-010-1851-4